The Innovative Training Networks (ITN) bring together universities, research centres and companies from different countries worldwide to train a new generation of researchers, in this case, Computational Oncology Researchers. This project is funded by European Union with 3.8mill€.
CONGRATULATIONS to David Posada’s Group, Evolutionary and Biomedical Genomics, that is directly involved in these “Early Stage Researcher” projects:
ESR 11: Estimation of tumour growth rates from NGS data
ESR 12: Mutational patterns and models within tumours.
More information about itn-CONTRA.
Doctor in Zoology, Full Professor of Genetics at the University of Vigo and coordinator of the Evolutionary Genomics Group (XB5) for CINBIO, David Posada González is the only Galician researcher to be awarded a Consolidator Grant, given by the European Research Council (ERC) in 2013. In 2003 he received a Ramón y Cajal grant, and in 2007 a Starting Grant, also given by the ERC. In addition, he is regarded as an ISI Highly Cited Researcher, according to Thomson Reuters, since 2003.
One of the lines of research of your group was awarded a Consolidator Grant by the ERC and it focuses on the creation of a theoretical and methodological framework allowing better comprehension of the evolution of carcinogenic tumour cells. What results do you hope to find in this area?
PHYLOCANCER is an ambitious 5 year project with 2 clear objectives: on one hand, to fine tune techniques for the study of individual genomes in tumour cells, and the development of bioinformatic methodologies for the mass analysis of genomic data. On the other, the generation of knowledge about evolutionary parameters in the life of a tumour, its history and how its characteristics develop (metastasis, growth rate, etc.) in each individual patient.
Francisco Javier Rodríguez Berrocal is a Full Professor of Biochemistry and Molecular Biology and secretary of the department of Biochemistry, Genetics and Immunology at the University of Vigo. In addition, he is also Principal Investigator for CINBIO’s Molecular Biomarkers group (BB1).
The BB1 group is multidisciplinary and it contains three different teams: Protein Biochemistry, Glycoproteomics, and Human Genetics. Despite this spread, they share a common aim: to find new genetic, proteic or glycidic markers, with the view of their potential application to various human pathologies.
What are the main lines of research being worked on, both individually and as a whole?
The three groups are working on the use and development of biological molecules as diagnostic, prognostic and disease monitoring markers in both humans and animals. We apply them to a wide range of diseases, from prevalent diseases such as cancer to rarer diseases such as ciliopathies. Read more
“We have a very high degree of internationalization, with collaborators in prestigious institutions from all five continents”
Jacobo de Uña-Álvarez, Ph.D in Mathematics, coordinates SIDOR (Statistical Inference, Decision and Operative Research group); a group created in 1998 at the University of Vigo which specialises in statistic models and methods. With a team made up of more than 30 researchers, SIDOR has been recognised as a Competitive Reference Research Group by the Xunta de Galicia since 2008.
What are the group’s main lines of research and what differences in approach do you have in comparison to similar groups? What are your main added values as a research group? (e.g. cross-disciplinary aspects of the group, established collaboration networks, etc.)
SIDOR group carries out basic research in the field of Statistics and Operations Research. Within biostatistics, our main lines of research are: survival analysis and multi-state models; the evaluation of diagnostic and prognostic tests; regression and prediction in high dimensional data and omic data; and multiple comparison methods.
SIDOR is the only research group with these capabilities in the south of Galicia. Besides carrying out basic research in Mathematics and developing statistical software, Read more
“We have the capability to take on complex problems and work in teams in which the coordination of professionals belonging to different fields of knowledge is essential”
Florentino Fdez-Riverola has a doctorate in Computer Engineering and is a member of the Department of Informatics at the University of Vigo, where he heads the Next Generation Computer Systems Group (SING), a multidisciplinary group which focuses on the research and development of new computer applications and methodologies.
“The quality and impact of our scientific output is our main endorsement as an elite research group”
The Colloid Chemistry Group was formed in 1996 not long after the opening of the Faculty of Chemistry at the University of Vigo.
The group is currently integrated into the CINBIO Biomedical Research Centre and is made up of 10 researchers, most of whom have a background in chemistry. The Principal Investigators are Jorge Pérez-Juste and Isabel Pastoriza and their research focuses on the synthesis, characterization and application of metal nanoparticles.
Meanwhile, Gustavo Bodelon, molecular biologist and postdoctoral researcher, offers a biological viewpoint to the group and his research is focused on plasmonic colloidal particles and their application in diagnostics and biodetection.
Doctor in Biology and tenured professor at the University of Vigo, José Antonio Lamas started the Neurosciences Group in 1997 in the Faculty of Biology. Last year, the group moved their activities to CINBIO’s facilities and it is from there that they are currently carrying out their research work.
“The study of genome mobility in oncogenic processes will revolutionise future diagnosis and treatment of cancer”
José Tubío has been part of the University of Vigo since 2016 and is one of the most important CINBIO researchers. With a background in Bioinformatics and Molecular Biology, he is a member of the International Cancer Genome Consortium and a recipient of an ERC Starting Grant. He currently leads the Mobile Genomics research group from which he coordinates research dealing with how certain sequences of DNA or tumour cells are mobilised and then cause the development of different types of cancer. Along with the Phylogenomics group led by David Posada, they set up the Evogenomics research group that currently has a team of around 20 people. 9 of the members from Evogenomics are part of the Mobile Genomics team. This multidisciplinary group is made up of bioinformaticians, mathematicians, pathologists, which provides a balance between the computational and the molecular biology areas.
Professor José Luis Legido is one of the 9 PIs of the Applied Physics 2 group at CINBIO and is also chairman of the Galician Thermal Peloid Society. Legido is in charge of a line of research focused on monitoring bacteria growth using microcalorimetric techniques, in which the effects of drugs on the bacteria are analysed. As a result of this research he has published eleven scientific articles, one book, three completed theses and one international patent in collaboration with the Vigo Hospital Complex.
We spoke to Africa González to find out first hand what CINBIO is, its potential and what it represents for the field of biomedics regionally, nationally and internationally.