The Immunology Group are working with International Iberian Nanotechnology Laboratory (INL) in “The development of a biosensor for early detection of peritoneal fibrosis induced by peritoneal dialysis in chronic renal failure patients”.
About 10% of the human population suffers of chronic renal failure, due to a progressive deterioration of kidney filtering capacity, and requires dialysis to remove toxic substances from blood. Currently there are two types of dialysis: haemodialysis, which involves three weekly visits of 3-5 hours each in hospital centers, or peritoneal dialysis (PD), which can be carried out in the patient’s residence and only takes 20 minutes, improving significantly his/her quality of life. However, PD is not widely employed as some patients under PD develop peritoneal fibrosis, which ultimately can lead to serious complications such as sclerotic peritonitis. The aim of this project is to identify biomarkers of fibrosis risk; once identified and validated, we will develop a diagnostic biosensor for the quantification of these biomarkers. This will allow the detection of early stages of fibrosis in patients under PD, in order to suspend the therapy in patients with such risk, increasing the safe use of PD.
The Colloid Chemistry Group are working with University of Minho, University of Santiago de Compostela, Universidade Católica Portuguesa, Instituto de Investigaciones Marinas. Consejo Superior de Investigaciones Científicas (IIM-CSIC), Instituto Superior de Engenharia do Porto, Novoa Santos Foundation, Instituto de Engenharia Biomédica (INEB) in “The network Bioengineering Institute for Healthy Aging (IBEROS)”.
The main objective of the IBEROS project is to promote research and innovation in the Euroregion that contributes with its results to improve the quality of life and health of the population, with a special focus on the diseases associated with aging. The Network Bioengineering Institute for Healthy Aging (IBEROS) is created as an interdisciplinary research center, to carry out excellent interdisciplinary research on the frontiers of engineering and life sciences in order to generate new knowledge by combining fields such as nanomedicine, tissue engineering, etc. in the field of health.