Vipul Bansal - CINBIO Seminar Programme 16 June 2023 Sala de seminarios da Torre CACTI
O 16 de xuño de 2023 o Dr. Vipul Bansal (RMIT University, Australia) ofrecerá o seminario NanoZymes as promising sensors, stimuli-responsive antimicrobial agents, and pro-drug therapies.
Será ás 10:00h na Sala de Seminarios da Torre CACTI.
Nanomaterials are well-known for their impressive catalytic activity. More recently, an increasing number of inorganic nanomaterials are being discovered to behave similarly to natural biomolecular enzymes. These are typically referred to as ‘NanoZymes’. This biomimetic activity of nanomaterials is establishing NanoZymes as a new subclass of artificial enzymes. Researchers have just begun to explore this unique property of nanomaterials for a range of applications from diagnostics to therapy. In particular, the focus of our team has been to (i) discover nanozyme activity in new materials; (ii) develop material synthesis approaches that show multiple or new enzyme-like activities in a single or hybrid material, e.g. nanozymes with apparent mimicry of diverse mammalian enzymes, including unique pan-glycosidases activity; (iii) understand the mechanism of nanozyme activity in nanomaterials; (iv) modulate nanozyme activity through external stimuli such as light; (v) use nanozymes to develop highly specific colorimetric biosensors; and (vi) explore the potential of nanozymes for therapeutic applications such as pro-drug therapy and photo-activatable antimicrobial agents. We have achieved this progress by studying the nanozyme activity of over 100 nanomaterials which has allowed us to draw some generalized trends about the behaviour of nanozymes. In this talk, we will discuss some of these developments made by our team. Some reflections from our other research that has seen a reasonably successful translation of nano-products from lab to clinic (biomedical imaging) and lab to society (wearable UV sensor) will also be provided.
Professor Vipul Bansal is the Director of the Sir Ian Potter NanoBioSensing Facility and a Professor of Nanobiotechnology in the Department of Applied Chemistry at RMIT University. He considers himself a social entrepreneur and is passionate about two things – mentoring the next generation of research leaders and facilitating the translation of nanotechnologies from the bench-side to the bedside. On the academic front, his contributions include 200+ publications with 15000+ citations and an h-index of 67. He has supervised 30+ PhD scholars, 5 of whom are in permanent academic positions, and the majority are well-established in industries.