Eventos
O xoves 23 maio de 2024 a Dra. Vanesa Álvarez Álvarez (Gene Regulatory Control in Disease Group at CIMUS, Universidade de Santiago de Compostela) ofrecerá o seminario "Deciphering ribosome specialisation during myelination", dentro do ciclo "CINBIO Seminar Programme".
Será ás 11:00h na Sala de seminarios de Torre CACTI.
ABSTRACT:
Axonal myelination is crucial to sustain neuronal function and health in the peripheral nervous system. This process requires massive synthesis of proteins and lipids to be continuously produced. Decades of research has uncovered a complex transcriptional program; in contrast, much less is known about the translational control of myelination. We examine the translation regulation of myelination studying ribosome specialization in Schwann cells. Specialized ribosomes are heterogenous ribosomes that have preferential regulation for any aspect of translational control. We identified several potential ribosome components that regulate translation in myelinating Schwann cells and potential pathways that control this differentiation process.
BIO:
Vanesa obtained her PhD at the Cancer Research Centre of Salamanca, at the University of Salamanca in 2017. There, she studied DNA damage tolerance pathways in eucharyotes. After obtaining her PhD, she moved as post-doc to the Gene Regulation and Expression department of the University of Dundee, where she focussed her research in DNA replication initiation, and chromatin replication and restoration. Her interest in gene expression regulation leaded her to Santiago de Compostela in 2023, to pursue a second Post-doc studying the differentiation process of Schwann cells at the Gene Regulatory Control in Disease Group at CIMUS, at the University of Santiago de Compostela.
