Research
- Retinoids and carotenoids: synthesis, study of metabolic routes and therapeutic usefulness.
- Bis-polyenic pyridinium salts formed by macular degeneration connected with aging.
- Nuclear receptors of retinoic acids (RAR, RXR): design and synthesis of selective modulators.
- Development of antivirals against SARS-CoV-2 with dihidroxicyclopentene skeletons.
- Development of synthetic routes to natural polyenes and polyene macrolactams using palladium-catalyzed cross-coupling reactions.
- Synthesis of epigenetic enzyme modulators (HDAC, Jmj-C HDM) based on natural products.
- Stereoselective synthesis of bioactive polyenes.
- Structural determination of natural products.
- Separation and purification of bioactive products.
- Synthesis of natural and synthetic copolymer hybrids (graft and block copolymers).Self-assembly of graft and block copolymers into solution-organized and surface-organized nanostructures.
- Structural characterization of polysaccharides (nuclear magnetic resonance and gel permeation chromatography).
- Computational study of transition metal catalysed reactions, organocatalysis and pericyclic polyene processes.
- Simulation of spectroscopic data of organic molecules.