Coñece ao #teamCINBIO: IN-ARMOR and ARTEMIS, two European projects 16 xullo 2024 Sala de seminarios da Torre CACTI

Programa Coñece ao #teamCINBIO

Briefing session on European projects

In this seminar, we will present two ongoing European projects involving TeamNanoTech and Hybrid Nanomaterials groups, exploring different applications of Nanotechnology. This session will consist of a series of short talks explaining the goals of these projects, as well as the role of CINBIO in their development.

The seminar will take place on Tuesday, July 16th, at 10.00 in the Seminar Room (Torre CACTI).

The projects are:

IN-ARMOR: Therapeutic Epigenetic Enhancement of Innate Immunity to Effectively Combat Antimicrobial Resistance

IN-ARMOR is a granted project by the European Health and Digital Executive Agency (HADEA) under HORIZON-HLTH-2022-DISEASE-06-two-stage call. Its target objective is to introduce a novel class of immune system inducers able to enhance the body’s own innate microbial defense mechanisms to combat antimicrobial resistance (AMR) and reduce the incidence of the 13 listed most dangerous infections (including 2 of the top 3 priority-1 infections).

IN-ARMOR will optimize an already developed drug platform using Computer Aided Drug Design, and in-silico approaches, in tandem with a nanotech-based drug delivery system for the first target indication. The developed therapy will be pre-clinically validated for safety and efficacy in-vitro and in vivo to complete all Investigational Medicinal Product requirements.

Upon completion, IN-ARMOR will be prepared for clinical validation. Upon commercialization, IN-ARMOR could potentially save more than 4Mn lives worldwide and result in the significant burden reduction of antibiotic development with long-term cost reduction impact of €107Bn, whilst reducing the global disease burden by 96.84Mn DALYs (total disease burden -enteric infections in 2019 in Disability-Adjusted Life Years-DALYs).


ARTEMIS: Molecular materials for on-chip integrated quantum light sources

ARTEMIS proposes fundamental research toward the development of integrable single and entangled photon sources based on metallorganic molecular compounds. The project is motivated by the urgent need for novel quantum sources with unprecedented versatility, flexibility and performance. This goal will be pursued by resorting to molecular materials, based on transition metal and/or lanthanide ions with organic moieties, characterized by tunable linear downshifted emission as well as non-linear optical properties enabling on-demand single photons and entangled photon pairs/triplets generation. Such flexible and processable metallorganic materials will replace traditional quantum photon sources based on bulk inorganic crystals allowing for the direct integration of wavelength-tunable quantum sources on current devices. The molecular quantum sources will be combined with suitable designed plasmonic supernanostructured cavities to achieve the highest optical enhancement. The proposed progress will be gained through cutting-edge synthesis techniques and advanced characterization methods integrated with nano-photonics engineering strategies. The devices and methods developed in this project will lead to photon sources with competitive performance in terms of coherence, efficiency, scalability, and cost. This will lead to a fundamental breakthrough in the development of quantum technologies, paving the way to bring them out of the laboratory into the real world.